Ayari Fuentes-Hernandez: Evolution of drug resistance in heterogeneous environments

Abstract (auf Englisch):

Our understanding of the evolutionary forces driving the adaptation of
antibiotic resistant bacteria is mostly based on the assumption of
constant, homogeneous environments. In this talk we will focus on
discussing how an environment with a heterogeneous temporal structure
imposes a dynamic range of selective pressures that can influence the
emergence and stability of drug resistance in microbial microcosms. To
achieve this goal, we will use data-­driven mathematical and
computational models combined with experimental evolution to study how
bacterial populations adapt to unpredictable and hostile environments.