Daniel Falush: The landscape of coadaptation in Vibrio parahaemolyticus
- Date: Nov 14, 2018
- Time: 11:00 AM - 12:00 PM (Local Time Germany)
- Speaker: Daniel Falush, University of Barth, UK
- More information on the speaker can be found here: https://researchportal.bath.ac.uk/en/persons/daniel-falush
- Location: MPI Plön
- Room: Lecture hall
- Host: Paul Rainey
Abstract
We exploit the nearly panmictic population
structure of
the gastric pathogen Vibrio parahaemolyticus to perform
a
genome-wide screen for coadapted genetic elements. The great
majority of
interactions that we detect are between accessory genes, many
involved in
carbohydrate transport and metabolism. The most
complex co-adaptations we
identify include hundreds of core genome SNPs and accessory
genome elements and
involve genes encoding lateral flagella and cell wall
biogenesis, implying that
several strategies have evolved for colonizing surfaces. Our
results provide
evidence that, as in human
relationships, coadaptation involves
progressively increasing levels of commitment, with the most
involved
interactions becoming irreversible and presaging speciation.