Korrespondierender Autor

Prof. Dr. Paul B. Rainey
Telefon:+49 4522 763-710

Evolutionary Biology • Genetics

Research report (imported) 2018 - Max Planck Institute for Evolutionary Biology

Exploring the limits of evolutionary forecasting

Authors

Rainey, Paul B.

Departments

Abteilung Mikrobielle Populationsbiologie

DOI

10.17617/1.6Y

Molecular biology can be repeated in the laboratory and in wild populations. This could mean that evolution might follow rules. Work with experimental bacterial populations suggests the genotype-to-phenotype map to be an important central contributor. Recent work using mathematical models and experimental evolution shows that short-term mechanistic-level predictions of mutational pathways to new adaptive phenotypes can be made. Future challenges stem from the current inability to a priori predict locus-specific mutational biases and environment-specific fitness effects.
 
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