Daniel Falush: The landscape of coadaptation in Vibrio parahaemolyticus

  • Datum: 14.11.2018
  • Uhrzeit: 11:00 - 12:00
  • Vortragende(r): Daniel Falush, University of Barth, UK
  • Weitere Informationen zum Sprecher finden Sie hier: https://researchportal.bath.ac.uk/en/persons/daniel-falush
  • Ort: MPI Plön
  • Raum: Hörsaal
  • Gastgeber: Paul Rainey

Abstract (auf Englisch):

We exploit the nearly panmictic population structure of the gastric pathogen Vibrio parahaemolyticus to perform a genome-wide screen for coadapted genetic elements. The great majority of interactions that we detect are between accessory genes, many involved in carbohydrate transport and metabolism. The most complex co-adaptations we identify include hundreds of core genome SNPs and accessory genome elements and involve genes encoding lateral flagella and cell wall biogenesis, implying that several strategies have evolved for colonizing surfaces. Our results provide evidence that, as in human relationships, coadaptation involves progressively increasing levels of commitment, with the most involved interactions becoming irreversible and presaging speciation.

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