Korrespondierender Autor

Prof. Dr. Paul B. Rainey
Telefon:+49 4522 763-710

Evolutionary Biology • Genetics

Research report (imported) 2019 - Max Planck Institute for Evolutionary Biology

Exploring the limits of evolutionary forecasting


Rainey, Paul B.


Abteilung Mikrobielle Populationsbiologie

Molecular biology can be repeated in the laboratory and in wild populations. This could mean that evolution might follow rules. Work with experimental bacterial populations suggests the genotype-to-phenotype map to be an important central contributor. Recent work using mathematical models and experimental evolution shows that short-term mechanistic-level predictions of mutational pathways to new adaptive phenotypes can be made. Future challenges stem from the current inability to a priori predict locus-specific mutational biases and environment-specific fitness effects.
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