Special Seminar - Robert Karn und Christina Laukaitis: The evolutionary history of the Abp gene family ex­­pansion in the genus Mus

  • Date: Mar 12, 2019
  • Time: 10:15 AM - 11:15 AM (Local Time Germany)
  • Speaker: Robert Karn and Christina Laukaitis, both from the University of Arizona, Tucson, USA
  • For more information on Robert Karn, please see: https://www.researchgate.net/profile/Robert_Karn // More information on Christina Laukaitis can be found here: https://deptmedicine.arizona.edu/profile/christina-m-laukaitis-md-phd-facp-facmg
  • Location: MPI Plön
  • Room: Lecture hall
  • Host: Kristian Ullrich


The mouse and rat genomes have independent expansions of their Androgen-binding protein (Abp) gene families, an extensive one in mouse and a more modest one in rat. Previous work that defined the Abp gene contents of these genomes postulated that the mouse expansion began in an ancestor of the genus Mus. We interrogated six wild-derived mouse genomes and identified eleven Abp genes in Mus pahari (Mp), 33 in M. caroli (Mc), 35 in M. spretus (Ms), 43 in Mus musculus domesticus (Mmd) 38 in M. m. musculus (Mmm) and 46 in M. m. castaneus (Mmc) and present evidence to support that hypothesis.

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