Special Seminar - Robert Karn und Christina Laukaitis: The evolutionary history of the Abp gene family expansion in the genus Mus
- Date: Mar 12, 2019
- Time: 10:15 AM - 11:15 AM (Local Time Germany)
- Speaker: Robert Karn and Christina Laukaitis, both from the University of Arizona, Tucson, USA
- For more information on Robert Karn, please see: https://www.researchgate.net/profile/Robert_Karn // More information on Christina Laukaitis can be found here: https://deptmedicine.arizona.edu/profile/christina-m-laukaitis-md-phd-facp-facmg
- Location: MPI Plön
- Room: Lecture hall
- Host: Kristian Ullrich
Abstract:
The mouse and rat genomes have independent expansions of their
Androgen-binding protein (Abp) gene families, an extensive one in
mouse and a more modest one in rat. Previous work that defined the
Abp gene contents of these genomes postulated that the mouse
expansion began in an ancestor of the genus Mus. We interrogated
six wild-derived mouse genomes and identified eleven Abp genes in
Mus pahari (Mp), 33 in M. caroli (Mc), 35 in M. spretus (Ms), 43
in Mus musculus domesticus (Mmd) 38 in M. m. musculus (Mmm) and 46
in M. m. castaneus (Mmc) and present evidence to support that
hypothesis.