Publications of Hildegard Uecker

Dewan, I.; Uecker, H.: Evolutionary rescue of bacterial populations by heterozygosity on multicopy plasmids. Journal of Mathematical Biology 90, 26 (2025)

Nyhoegen, C.; Bonhoeffer, S.; Uecker, H.: The many dimensions of combination therapy: How to combine antibiotics to limit resistance evolution. Evolutionary Applications 17 (8), e13764 (2024)

Dewan, I.; Uecker, H.: Is the distribution of plasmid lengths bimodal? Plasmid 129, 102721 (2024)

Geoffroy, F.; Uecker, H.: Limits to evolutionary rescue by conjugative plasmids. Theoretical Population Biology 154, pp. 102 - 117 (2023)

Garoña, A.; Santer, M.; Hülter, N. F.; Uecker, H.; Dagan, T.: Segregational drift hinders the evolution of antibiotic resistance on polyploid replicons. PLoS Genetics 19 (8), e1010829 (2023)

Dewan, I.; Uecker, H.: A mathematician’s guide to plasmids: an introduction to plasmid biology for modellers. Microbiology 169, 001362 (2023)

Nyhoegen, C.; Uecker, H.: Sequential antibiotic therapy in the laboratory and in the patient. Interface: Journal of the Royal Society 20, 2022793 (2023)

Santer, M.; Kupczok, A.; Dagan, T.; Uecker, H.: Fixation dynamics of beneficial alleles in prokaryotic polyploid chromosomes and plasmids. Genetics 222 (2), iyac121 (2022)

Traulsen, A.; Gokhale, C. S.; Shah, S.; Uecker, H.: The Covid-19 pandemic: basic insights from basic mathematical models. NAL-live / Deutsche Akademie der Naturforscher Leopoldina e. V. - Nationale Akademie der Wissenschaften 3, 01000 (2022)

Geoffroy, F.; Traulsen, A.; Uecker, H.: Vaccination strategies when vaccines are scarce: on conflicts between reducing the burden and avoiding the evolution of escape mutants. Interface: Journal of the Royal Society 19, 20220045 (2022)

Uecker, H.; Bonhoeffer, S.: Antibiotic treatment protocols revisited: the challenges of a conclusive assessment by mathematical modelling. Journal of the Royal Society Interface 18 (181), 20210308 (2021)

Czuppon, P.; Blanquart, F.; Uecker, H.; Débarre, F.: The effect of habitat choice on evolutionary rescue in subdivided populations. The American Naturalist 197 (6), pp. 625 - 643 (2021)

Lagator, M.; Uecker, H.; Neve, P.: Adaptation at different points along antibiotic concentration gradients. Biology Letters 17 (5), 20200913 (2021)

Santer, M.; Uecker, H.: Evolutionary rescue and drug resistance on multicopy plasmids. Genetics 215 (2) (2020)

Scire, J.; Hozé, N.; Uecker, H.: Aggressive or moderate drug therapy for infectious diseases? Trade-offs between different treatment goals at the individual and population levels. PLoS Computational Biology 15 (8), e1007223 (2019)

Uecker, H.: Effectively Evolution-proof Antibiotics? Trends in Microbiology 26 (12), pp. 969 - 970 (2018)

Tepekule, B.; Uecker, H.; Derungs, I.; Frenoy, A.; Bonhoeffer, S.: Modeling antibiotic treatment in hospitals: a systematic approach shows benefits of combination therapy over cycling, mixing, and mono-drug therapies. PLoS Computational Biology 13 (9), e1005745 (2017)

Uecker, H.: Evolutionary rescue in randomly mating, selfing, and clonal populations. Evolution 71 (4), pp. 845 - 858 (2017)

Uecker, H.; Bonhoeffer, S.: Modeling antimicrobial cycling and mixing: Differences arising from an individual-based versus a population-based perspective. Mathematical Biosciences 294, pp. 85 - 91 (2017)

Uecker, H.; Hermisson, J.: The role of recombination in evolutionary rescue. Genetics 202 (2), pp. 721 - 732 (2016)