Suchergebnisse

Lenz, T. L.: Adaptive value of novel MHC immune gene variants. Proceedings of the National Academy of Sciences of the United States of America 115 (7), S. 1414 - 1416 (2018)

Krause-Kyora, B.; Nutsua, M.; Boehme, L.; Pierini, F.; Pedersen, D. D.; Kornell, S.-C.; Drichel, D.; Bonazzi, M.; Möbus, L.; Tarp, P. et al.; Susat, J.; Bosse, E.; Willburger, B.; Schmidt, A. H.; Sauter, J.; Franke, A.; Wittig, M.; Caliebe, A.; Nothnagel, M.; Schreiber, S.; Boldsen, J. L.; Lenz, T. L.; Nebel, A.: Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans. Nature Communications 9, 1569 (2018)

Calvignac-Spencer, S.; Lenz, T. L.: The one past health workshop: connecting ancient DNA and zoonosis research. Bioessays 39 (7), 1700075 (2017)

Kaufmann, J.; Lenz, T. L.; Kalbe, M.; Milinski, M.; Eizaguirre, C.: A field reciprocal transplant experiment reveals asymmetric costs of migration between lake and river ecotypes of three-spined sticklebacks (Gasterosteus aculeatus). Journal of Evolutionary Biology 30 (5), S. 938 - 950 (2017)

Lenz, T. L.; Spirin, V.; Jordan, D. M.; Sunyaev, S. R.: Excess of deleterious mutations around HLA genes reveals evolutionary cost of balancing selection. Molecular Biology and Evolution 33 (10), S. 2765 - 2766 (2016)

Huang, Y.; Chain, F. J. J.; Panchal, M.; Eizaguirre, C.; Kalbe, M.; Lenz, T. L.; Samonte, I. E.; Stoll, M.; Bornberg-Bauer, E.; Reusch, T. B. H. et al.; Milinski, M.; Feulner, P. G. D.: Transcriptome profiling of immune tissues reveals habitat-specific gene expression between lake and river sticklebacks. Molecular Ecology 25 (4), S. 943 - 958 (2016)

Savova, V.; Chun, S.; Sohail, M.; McCole, R. B.; Witwicki, R.; Gai, L.; Lenz, T. L.; Wu, C.-t.; Sunyaev, S. R.; Gimelbrant, A. A.: Genes with monoallelic expression contribute disproportionately to genetic diversity in humans. Nature Genetics, 3493 (2016)

McLaren, P. J.; Coulonges, C.; Bartha, I.; Lenz, T. L.; Deutsch, A. J.; Bashirova, A.; Buchbinder, S.; Carrington, M. N.; Cossarizza, A.; Dalmau, J. et al.; Luca, A. D.; Goedert, J. J.; Gurdasani, D.; Haas, D. W.; Herbeck, J. T.; Johnson, E. O.; Kirk, G. D.; Lambotte, O.; Luo, M.; Mallal, S.; van Manen, D.; Martinez-Picado, J.; Meyer, L.; Miro, J. M.; Mullins, J. I.; Obel, N.; Poli, G.; Sandhu, M. S.; Schuitemaker, H.; Shea, P. R.; Theodorou, I.; Walker, B. D.; Weintrob, A. C.; Winkler, C. A.; Wolinsky, S. M.; Raychaudhuri, S.; Goldstein, D. B.; Telenti, A.; de Bakker, P. I. W.; Zagury, J.-F.; Fellay, J.: Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load. Proceedings of the National Academy of Sciences of the United States of America (2015)

Lenz, T. L.: Transcription in space – environmental vs. genetic effects on differential immune gene expression. Molecular Ecology 24 (18), S. 4583 - 4585 (2015)

Lenz, T. L.; Deutsch, A. J.; Han, B.; Hu, X.; Okada, Y.; Eyre, S.; Knapp, M.; Zhernakova, A.; Huizinga, T. W. J.; Abecasis, G. et al.; Becker, J.; Boeckxstaens, G. E.; Chen, W.-M.; Franke, A.; Gladman, D. D.; Gockel, I.; Gutierrez-Achury, J.; Martin, J.; Nair, R. P.; Nöthen, M. M.; Onengut-Gumuscu, S.; Rahman, P.; Rantapää-Dahlqvist, S.; Stuart, P. E.; Tsoi, L. C.; van Heel, D. A.; Worthington, J.; Wouters, M. M.; Klareskog, L.; Elder, J. T.; Gregersen, P. K.; Schumacher, J.; Rich, S. S.; Wijmenga, C.; Sunyaev, S. R.; de Bakker, P. I. W.; Raychaudhuri, S.: Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases. Nature Genetics 47 (9), S. 1085 - 1090 (2015)

Hu, X.; Deutsch, A. J.; Lenz, T. L.; Onengut-Gumuscu, S.; Han, B.; Chen, W.-M.; Howson, J. M. M.; Todd, J. A.; de Bakker, P. I. W.; Rich, S. S. et al.; Raychaudhuri, S.: Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk. Nature Genetics 47 (8), S. 898 - 905 (2015)

Feulner, P. G. D.; Chain, F. J. J.; Panchal, M.; Huang, Y.; Eizaguirre, C.; Kalbe, M.; Lenz, T. L.; Samonte, I. E.; Stoll, M.; Bornberg-Bauer, E. et al.; Reusch, T. B. H.; Milinski, M.: Genomics of divergence along a continuum of parapatric population differentiation. PLoS Genetics 11 (2), e1004966 (2015)

Kaufmann, J.; Eizaguirre, C.; Milinski, M.; Lenz, T. L.: The contribution of post-copulatory mechanisms to incipient ecological speciation in sticklebacks. Biology Letters 11 (1), 20140933 (2015)

Chain, F. J. J.; Feulner, P. G. D.; Panchal, M.; Eizaguirre, C.; Samonte, I. E.; Kalbe, M.; Lenz, T. L.; Stoll, M.; Bornberg-Bauer, E.; Milinski, M. et al.; Reusch, T. B. H.: Extensive copy-number variation of young genes across stickleback populations. PLoS Genetics 10 (12), e1004830 (2014)

Kaufmann, J.; Lenz, T. L.; Milinski, M.; Eizaguirre, C.: Experimental parasite infection reveals costs and benefits of paternal effects. Ecology Letters 17 (11), S. 1409 - 1417 (2014)

Seim, I.; Fang, X.; Xiong, Z.; Lobanov, A. V.; Huang, Z.; Ma, S.; Feng, Y.; Turanov, A. A.; Zhu, Y.; Lenz, T. L. et al.; Gerashchenko, M. V.; Fan, D.; Yim, S. H.; Yao, X.; Jordan, D.; Xiong, Y.; Ma, Y.; Lyapunov, A. N.; Chen, G.; Kulakova, O. I.; Sun, Y.; Lee, S.-G.; Bronson, R. T.; Moskalev, A. A.; Sunyaev, S. R.; Zhang, G.; Krogh, A.; Wang, J.; Gladyshev, V. N.: Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii. Nature Communications 4, 2212 (2013)

Lenz, T. L.; Eizaguirre, C.; Kalbe, M.; Milinski, M.: Evaluating patterns of convergent evolution and trans-species polymorphism at MHC immunogenes in two sympatric stickleback species. Evolution 67 (8), S. 2400 - 2412 (2013)

Lenz, T. L.; Mueller, B.; Trillmich, F.; Wolf, J. B. W.: Divergent allele advantage at MHC-DRB through direct and maternal genotypic effects and its consequences for allele pool composition and mating. Proceedings of the Royal Society B: Biological Sciences 280 (1762), 20130714 (2013)

Feulner, P. G. D.; Chain, F. J. J.; Panchal, M.; Eizaguirre, C.; Kalbe, M.; Lenz, T. L.; Mundry, M.; Samonte, I. E.; Stoll, M.; Milinski, M. et al.; Reusch, T. B. H.; Bornberg-Bauer, E.: Genome-wide patterns of standing genetic variation in a marine population of three-spined sticklebacks. Molecular Ecology 22 (3), S. 635 - 649 (2013)

Lenz, T. L.; Eizaguirre, C.; Rotter, B.; Kalbe, M.; Milinski, M.: Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome-wide digital gene expression analysis. Molecular Ecology 22 (3), S. 774 - 786 (2013)